Cannabinoids
Cannabis, synthetic cannabinoids (K2/Spice), high-potency concentrates, and unregulated hemp-derived compounds (HHC, Δ-8).
Latest reporting
The DEA Rescheduling Hearing Excluded the People It Was About — Don't Call the Outcome Legitimate Yet
Post-hearing briefs are due today in the DEA's marijuana rescheduling proceeding — a closed-door, non-livestreamed hearing that excluded reform advocates and now hands the real decision to a single political appointee.
Weed Is More Popular Than the Politicians Running From It
Cannabis ballot fights in Massachusetts and Idaho, plus governor's races in Kansas and Iowa, show voters running ahead of their own parties on legalization.
The Federal Hemp Ban Isn't About Weed. It's About Who Gets to Decide What Counts as Medicine.
A federal redefinition of hemp will make roughly 95% of hemp-derived THC products federally illegal on December 11. A Texas smoke shop owner and the general counsel of the U.S. Hemp Roundtable explain what's actually at stake.
Through eight lenses
Science
CB1/CB2 receptor system, THC partial agonist, CBD complex pharmacology, synthetic cannabinoids as full agonists.
Biology
Acute cognitive effects, cardiovascular risk underappreciated, cannabinoid hyperemesis syndrome, dose-response with potency.
Cannabis Isn't One Story Anymore. It's a Psychosis Risk, a Drinking Substitute, and a Treatment Gap — All at Once.
Aug 3Cannabis Got Roughly Ten Times Stronger Since the 1990s. Nobody Rewrote the Warning Label to Match.
Jul 24Daily Cannabis Use Raises Psychosis Risk. It Still Won't Fix Your Anxiety.
Jul 21
Psychology
Cannabis Use Disorder is real (~9% lifetime risk among users, higher w/ daily use), psychosis risk in predisposed individuals with high-potency concentrates.
Cannabis Isn't One Story Anymore. It's a Psychosis Risk, a Drinking Substitute, and a Treatment Gap — All at Once.
Aug 3Your Brain Chemistry May Decide Whether Cannabis Triggers Psychosis. A New Scan Shows How.
Jul 12The Government Is Fighting a Drug-Testing Company in Court Over Whether Weed Is Still a Schedule I Drug
Jul 4
Policy
Federal schedule I, state-by-state patchwork, 2018 Farm Bill loophole birthing Delta-8/HHC/THC-O.
Trends
Potency has tripled since 2000; daily-use rates rising; vaping concentrates among youth.
Treatment
No FDA-approved meds; CBT, MET, contingency management.
Harm Reduction
Start low/go slow, avoid mixing, be cautious with edibles (delayed onset → redosing), synthetic cannabinoid (K2) toxicity is qualitatively different and severe.
Cannabis Isn't One Story Anymore. It's a Psychosis Risk, a Drinking Substitute, and a Treatment Gap — All at Once.
Aug 3Cannabis Got Roughly Ten Times Stronger Since the 1990s. Nobody Rewrote the Warning Label to Match.
Jul 24The Government Is Fighting a Drug-Testing Company in Court Over Whether Weed Is Still a Schedule I Drug
Jul 4